方法一：

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1、設(shè)置/etc/grub.conf文件，添加 transparent_hugepage=never ，在系統(tǒng)啟動(dòng)是禁用

[root@hbdw1 ~]# cat /etc/grub.conf 
# grub.conf generated by anaconda
#
# Note that you do not have to rerun grub after making changes to this file
# NOTICE: You have a /boot partition. This means that
# all kernel and initrd paths are relative to /boot/, eg.
# root (hd0,0)
# kernel /vmlinuz-version ro root=/dev/sda2
# initrd /initrd-[generic-]version.img
#boot=/dev/sda
default=0
timeout=5
splashimage=(hd0,0)/grub/splash.xpm.gz
hiddenmenu
title Red Hat Enterprise Linux 6 (2.6.32-573.el6.x86_64)
root (hd0,0)
kernel /vmlinuz-2.6.32-573.el6.x86_64 ro root=UUID=57f7184b-2dec-43b1-b0cd-9862a4b42cfe rd_NO_LUKS KEYBOARDTYPE=pc KEYTABLE=us LANG=en_US.UTF-8 rd_NO_MD SYSFONT=latarcyrheb-sun16 rd_NO_LVM rhgb quiet rd_NO_DM rhgb quiet memmap=0x2000000$0x3E000000 nmi_watchdog=2 crashkernel=256M-:256M printk.time=1 console=ttyS0,115200 console=tty0 transparent_hugepage=never ##添加到 tty0 后面，注意留一個(gè)空格 
initrd /initramfs-2.6.32-573.el6.x86_64.img

2、 重啟服務(wù)器

3、檢查是否關(guān)閉

# grep AnonHugePages /proc/meminfo

If the output contains a line like "AnonHugepages: 
xxxx kB", with a value > 0kB, the kernel is using Transparent HugePages.

方法二：

1、編輯 /etc/rc.local 添加如下內(nèi)存

[root]# cat /etc/rc.local
if test -f /sys/kernel/mm/transparent_hugepage/enabled; then
echo never > /sys/kernel/mm/transparent_hugepage/enabled
fi
if test -f /sys/kernel/mm/transparent_hugepage/defrag; then
echo never > /sys/kernel/mm/transparent_hugepage/defrag
fi

2、 重啟服務(wù)器

3、檢查是否關(guān)閉

# grep AnonHugePages /proc/meminfo

If the output contains a line like "AnonHugepages: 
xxxx kB", with a value > 0kB, the kernel is using Transparent HugePages.

補(bǔ)充：

1：從RedHat 6, OEL 6, SLES 11 and UEK2 kernels 開始，系統(tǒng)缺省會(huì)啟用 Transparent HugePages ：用來(lái)提高內(nèi)存管理的性能透明大頁(yè)（Transparent HugePages ）和之前版本中的大頁(yè)功能上類似。主要的區(qū)別是：Transparent HugePages 可以實(shí)時(shí)配置，不需要重啟才能生效配置；

2：Transparent Huge Pages在32位的RHEL 6中是不支持的。

Transparent Huge Pages are not available on the 32-bit version of RHEL 6.

3： ORACLE官方不建議我們使用RedHat 6, OEL 6, SLES 11 and UEK2 kernels 時(shí)的開啟透明大頁(yè)（Transparent HugePages ）， 因?yàn)橥该鞔箜?yè)（Transparent HugePages ） 存在一些問(wèn)題：

1.在RAC環(huán)境下 透明大頁(yè)（Transparent HugePages ）會(huì)導(dǎo)致異常節(jié)點(diǎn)重啟，和性能問(wèn)題；

2.在單機(jī)環(huán)境中，透明大頁(yè)（Transparent HugePages ） 也會(huì)導(dǎo)致一些異常的性能問(wèn)題；

Transparent HugePages memory is enabled by default with Red Hat Enterprise Linux 6, SUSE Linux Enterprise Server 11, and Oracle Linux 6 with earlier releases of Oracle Linux Unbreakable Enterprise Kernel 2 (UEK2) kernels. Transparent HugePages memory is disabled in later releases of Oracle Linux UEK2 kernels.Transparent HugePages can cause memory allocation delays during runtime. To avoid performance issues, Oracle recommends that you disable Transparent HugePages on all Oracle Database servers. Oracle recommends that you instead use standard HugePages for enhanced performance.Transparent HugePages memory differs from standard HugePages memory because the kernel khugepaged thread allocates memory dynamically during runtime. Standard HugePages memory is pre-allocated at startup, and does not change during runtime.

Starting with RedHat 6, OEL 6, SLES 11 and UEK2 kernels, Transparent HugePages are implemented and enabled (default) in an attempt to improve the memory management. Transparent HugePages are similar to the HugePages that have been available in previous Linux releases. The main difference is that the Transparent HugePages are set up dynamically at run time by the khugepaged thread in kernel while the regular HugePages had to be preallocated at the boot up time. Because Transparent HugePages are known to cause unexpected node reboots and performance problems with RAC, Oracle strongly advises to disable the use of Transparent HugePages. In addition, Transparent Hugepages may cause problems even in a single-instance database environment with unexpected performance problems or delays. As such, Oracle recommends disabling Transparent HugePages on all Database servers running Oracle.

4：安裝Vertica Analytic Database時(shí)也必須關(guān)閉透明大頁(yè)功能